Ok

Respectfully acknowledging different perspectives is key to maintaining productive conversations.

Fair enough. Nice weather we're having, isn't it?

We're not disagreeing. I'm explaining why you're wrong.

alright, have a nice day

Let’s not

After a quick mental note making sure to never ever ever mention this subject with said disagreeable peoples, I would then hope we can continue our friendship based on mutual respect, awe, and respect of our differences.

alright. wanna hear about the book I'm reading on coroners?

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Just disengage. People usually say this when they're getting tired of the convo. It's frustrating but pushing is just gonna annoy them and galvanize their position.

Depends on what it is but a shrug does the trick.