IAmDavidGurney OP t1_j5b32y4 wrote

Its interesting situation was caused by the USA and UK deciding that the 49th parallel would be the border between the USA and Canada.

Students from fourth grade onward must be driven 40 minutes into Canada and then into Washington state to go to school. Imagine crossing two international borders just to go to school. That's four border crossings a day and twenty crossings a week lol.


IAmDavidGurney OP t1_j4t3u7f wrote

It was originally part of Manhattan Island. Then it became an island in the Harlem river in 1895 due to the Harlem Ship Canal. Finally, it became connected to the Bronx by filling landfill into the space in the river between Marble Hill and the Bronx in 1914.

Also, fun fact: the Bronx is the only NYC borough that is connected to the mainland United States.


IAmDavidGurney OP t1_j2cqzgy wrote

It's sorta like alcohol but not really. It's much more euphoric and has a prosocial/empathogenic quality. It can be stimulating in lower doses and sedating in higher doses. It's basically non toxic and produces no hangover.

Taking too much is a danger since it's potent. That's why you need a syringe to measure the dose.


IAmDavidGurney OP t1_j2cqtt4 wrote

Yes, but I meant that the GHB receptor is there to have endogenous GHB bind to it. Nicotinic acetylcholine receptors are designed to have acetylcholine bind to them. Nicotine binds to them but the receptor isn't there for nicotine since it isn't naturally in the brain. Opiate receptors are there to have endorphins bind to them, not exogenous opioids. Cannabinoid receptors are meant for endocannabinoids like anandamide, not THC.

Yeah, these drugs bind to those receptors but the receptors are there for naturally occurring neurotransmitters, not the drug. What's interesting about GHB is that its receptor is designed for the brains GHB.


IAmDavidGurney OP t1_j2cq00s wrote

My point was that GHB has it's own receptor that it binds too. IE the GHB receptor is designed to have endogenous GHB bind to it. The cannabinoid receptors are designed for endocannabinoids like anandamide, not THC or CBD which the body does not produce.


IAmDavidGurney OP t1_j2cn1ls wrote

Of course the dose in natural products is so low you would never feel the effects.

Also, not only is GHB naturally produced in the brain but it also has it's own receptor, the GHB receptor. I don't know of any other drugs that have their own receptor. There is no THC or DMT receptor. They bind to other receptors designed for neurotransmitters.


IAmDavidGurney OP t1_j1c9bxb wrote

He performed this brave/suicidal action because he had recently been demoted from sergeant to private. After his death, he was posthumously restored to sergeant.

> Being of recent German-American heritage, Gunther did not automatically enlist in the armed forces as many others did soon after the United States declared war on Germany in April 1917. In September 1917, he was drafted and quickly assigned to the 313th Infantry Regiment, nicknamed "Baltimore's Own"; it was part of the larger 157th Brigade of the 79th Infantry Division. Promoted as a supply sergeant, he was responsible for clothing in his military unit, and arrived in France in July 1918 as part of the incoming American Expeditionary Forces. A critical letter home, in which he reported on the "miserable conditions" at the front and advised a friend to try anything to avoid being drafted, was intercepted by the Army postal censor. As a result, he was demoted from sergeant to private.[3][6]

> Gunther's unit, Company 'A', arrived at the Western Front on September 12, 1918. Like all Allied units on the front of the Meuse-Argonne Offensive, it was still embroiled in fighting on the morning of November 11.[8] The Armistice with Germany was signed by 5:00 a.m., local time, but it would not come into force until 11:00 a.m. Gunther's squad approached a roadblock of two German machine guns in the village of Chaumont-devant-Damvillers near Meuse, in Lorraine. Gunther got up, against the orders of his close friend and now sergeant, Ernest Powell, and charged with his bayonet. The German soldiers, already aware of the Armistice that would take effect in one minute, tried to wave Gunther away. He kept going and fired "a shot or two".[3] When he got too close to the machine guns, he was shot in a short burst of automatic fire and killed instantly.[9] The writer James M. Cain, then a reporter for the local daily newspaper, The Sun, interviewed Gunther's comrades afterward and wrote that "Gunther brooded a great deal over his recent reduction in rank, and became obsessed with a determination to make good before his officers and fellow soldiers".[3] > > American Expeditionary Forces commanding General John J. Pershing's "Order of The Day" on the following day specifically mentioned Gunther as the last American killed in the war.[9] The Army posthumously restored his rank of sergeant and awarded him a Divisional Citation for Gallantry in Action and the Distinguished Service Cross. Several years later, a post, number 1858 of the Veterans of Foreign Wars in east Baltimore, was named after him.[2][3][10] The VFW Post honoring the name of Sergeant Gunther has since ceased to exist. > > Gunther's remains were returned to the United States in 1923 after being exhumed from a military cemetery in France, and buried at the Most Holy Redeemer Cemetery in Baltimore.[2] Subsequent investigations revealed that on the last day of World War I, during the armistice negotiations in the railroad cars encampment at the Compiegne Forest, French commander-in-chief Marshal Foch refused to accede to the German negotiators' request to declare an immediate ceasefire or truce so that there would be no more useless waste of lives among the common soldiers. The failure to declare a truce, even between the signing of the documents for the Armistice and its entry into force "at the eleventh hour of the eleventh day of the eleventh month", caused about 11,000 additional men to be wounded or killed – far more than usual, according to the military statistics.[11] > >